Cotton is an important cash crop in Pakistan with robust backward and forward linkages in the economy. Dismal progress of the crop during recent years has raised questions and concerns to the research, development and relevant agricultural policies landscape of the country. This has remained quite diverse during recent regimes, ranging from support prices, import, export and production subsidies, trade restrictions, technology acquisition, and protection from land distribution to fragmentation. Policy Analysis Matrix (PAM) can be an appropriate tool to estimate the effect of agricultural policies on production systems and farmers’ decisions. Primary data will be collected from Punjab, Sindh and Balochistan provinces to develop PAM. Similarly, focus group discussions will also be conducted with key stakeholders to refine policy scenarios to enhance the competitiveness and efficiency of the crop, especially in the wake of water and climate change scenarios till the mid-century.